Abigale™ (Estradiol Hemihydrate / Norethisterone Acetate Tablets)

Abigale™ from Xiromed is a combination hormone therapy tablet formulated with Estradiol Hemihydrate and Norethisterone Acetate. Supplied in a convenient 1mg/0.5mg strength, each pack contains three blister cards of 28 tablets to support continuous therapy schedules.

Pharmacies, distributors, and healthcare buyers can rely on Abigale™ as part of Xiromed’s growing portfolio of quality generic medications. Every batch is manufactured to meet stringent regulatory standards, giving your supply chain a product you can trust for consistency and availability.

Use the details below to confirm specifications, verify the NDC, and align this product with your inventory needs.

Active Ingredients and Their Roles

The strength of any combination HRT product lies in how its ingredients work together. Abigale™ combines two well-established hormones, each with a defined purpose within the regimen.

Estradiol Hemihydrate (1 mg) is the estrogen component. As the body’s natural estrogen production declines, symptoms tied to estrogen deficiency can follow. Estradiol Hemihydrate supplies a form of estrogen that helps address this shortfall, forming the primary therapeutic driver of the formulation.

Norethisterone Acetate (0.5 mg) is the progestogen component. In women with an intact uterus, unopposed estrogen can affect the endometrium — the lining of the uterus. Norethisterone Acetate is included to help protect that lining during estrogen therapy. This pairing reflects standard clinical practice for continuous combined HRT and is a key reason the two ingredients appear together in a single tablet.

By delivering both hormones in one daily oral dose, the formulation streamlines the regimen. Patients take one tablet rather than managing multiple products, and dispensers handle a single SKU rather than coordinating separate items.

Indications and Use

Abigale™ belongs to the combined hormone replacement therapy category and is intended for use under the direction of a qualified healthcare professional. Products of this type are typically prescribed for:

• Relief of symptoms associated with estrogen deficiency
• Continuous combined hormone replacement therapy in appropriate patients with an intact uterus

Prescribing decisions, dosing, patient selection, and duration of treatment should always follow the approved product labeling and the clinical judgment of the treating physician. This description is provided for licensed professionals and authorized trade partners and is not a substitute for the full prescribing information.

Key Product Details

Attribute	Detail
Strength	1 mg / 0.5 mg
Pack Size	3 x 28 tablets
NDC	70700-330-85
Dosage Form	Oral tablet
Brand	Abigale™
Supplier	Xiromed

How It Works / Active Ingredients

This product combines two active hormones that work together within a continuous combined regimen:

• Estradiol Hemihydrate — a form of estrogen that replaces the natural estrogen the body produces less of over time. It supports the primary hormonal component of therapy.
• Norethisterone Acetate — a progestogen included to help protect the endometrium (the lining of the uterus) during estrogen therapy.

Together, these ingredients deliver a fixed-dose combination in a single daily tablet, simplifying the regimen for both dispensers and end users.

Indications / Uses

This product is a combined hormone replacement therapy (HRT) product. It is intended for use under the direction of a qualified healthcare professional. Typical indications for products in this category include:

• Relief of symptoms associated with estrogen deficiency
• Continuous combined hormone replacement therapy in appropriate patients

Prescribing decisions, dosing, and patient suitability should always follow the approved product labeling and the judgment of the treating clinician.

Product Specifications

Specification	Value
Product Name	Abigale™
Generic Name	Estradiol Hemihydrate / Norethisterone Acetate Tablets
Strength	1 mg / 0.5 mg
Package Configuration	3 x 28 tablet blister pack
NDC	70700-330-85
Route of Administration	Oral
Product Category	Combined hormone replacement therapy
Storage	Store per approved product labeling

Frequently Asked Questions

What is the NDC for Abigal™ 1mg/0.5mg?
The National Drug Code for this Abigale™ configuration is 70700-330-85, supplied in a 3 x 28 tablet pack.

How many tablets come in each Abigale™ pack?
Each pack holds 84 tablets total, arranged as three blister cards of 28 tablets each, supporting a continuous therapy schedule.

What active ingredients does Abigale™ contain?
Abigale™ contains two active ingredients: Estradiol Hemihydrate 1 mg and Norethisterone Acetate 0.5 mg per tablet.

Is Abigale™ a brand or generic product?
Abigal™ is a branded generic offered by Xiromed, providing a quality-manufactured alternative for hormone replacement therapy.

Who should order Abigal™ through Xiromed?
Pharmacies, wholesalers, and healthcare distributors can source Abigale™ directly through Xiromed for reliable supply and verified specifications.

Compliance / Disclaimer

This information is intended for licensed healthcare professionals, pharmacies, and authorized distributors. Abigal™ is a prescription product and should be used only as directed by a qualified healthcare provider in accordance with the approved product labeling. Product availability, specifications, and regulatory status may vary by region. Please refer to the full prescribing information before dispensing.